Lymphoscintigraphy Sentinel Node Mapping

Overview

Lymphoscintigraphy maps lymphatic flow and sentinel nodes using injected radiocolloids for surgical planning and lymphedema assessment.

Technique

Dynamic and static imaging with planar or SPECT CT localizes sentinel nodes and evaluates lymphatic obstruction.

Clinical Uses

Sentinel lymph node mapping in oncology and evaluation of lymphedema.

Limitations and Safety

Spatial resolution limited. Combined modalities improve localization for surgery.

Positron Emission Tomography PET

Overview

PET images physiologic and metabolic processes using radiotracers such as FDG and detects areas of altered metabolism with high sensitivity.

Technique

Radiotracer selection uptake time and attenuation correction are critical. PET is often combined with CT or MRI for anatomic localization.

Clinical Uses

Oncology staging and response assessment infection and inflammation imaging and neurologic metabolic studies.

Limitations and Safety

Radiation exposure from radiotracers and CT component. False positives from inflammatory uptake require clinical correlation.

Single Photon Emission Computed Tomography SPECT

Overview

SPECT acquires gamma emissions from radiotracers to reconstruct three dimensional functional images often combined with CT for localization.

Technique

Collimator choice acquisition orbit and reconstruction parameters influence resolution and sensitivity.

Clinical Uses

Cardiac perfusion imaging bone scans infection imaging and certain neurologic studies.

Limitations and Safety

Lower spatial resolution than PET. Radiotracer selection and timing affect diagnostic yield.