Tag Archives: imaging

UK Medicines and Healthcare Products Regulatory Agency MHRA Medical Device Regulation
9
Feb

Overview

MHRA oversees device conformity clinical investigations and postmarket vigilance for imaging modalities in the United Kingdom.

Modality Focus

Guidance covers CT MRI ultrasound mammography and nuclear medicine device safety and clinical investigation requirements.

Brexit Transition

MHRA has established UK specific regulatory pathways and guidance following EU transition.

Clinical Impact

Manufacturers and clinical users follow MHRA guidance for device placement and safety in UK imaging services.

Technetium 99m sulfur colloid
7
Feb

Overview

Technetium 99m sulfur colloid is a radiolabeled colloid used in nuclear medicine to image liver, spleen and bone marrow distribution and for gastric emptying studies.

Properties

Colloidal particles labeled with Tc 99m emit gamma photons detected by gamma cameras; particle size influences biodistribution.

Uses

Used for liver spleen scintigraphy, sentinel node mapping in some protocols and gastric emptying or gastric mucosa imaging.

Safety

Radiation exposure is low but present; follow nuclear medicine radiation safety, pregnancy screening and local regulatory requirements.

Paul Lauterbur
4
Feb

Overview

Paul Lauterbur introduced the concept of spatial encoding using magnetic field gradients enabling two dimensional and three dimensional MRI.

Key Contributions

Demonstrated how gradient based encoding produces images from nuclear magnetic resonance signals and enabled clinical MRI development.

Impact on Medicine

Lauterbur’s innovations allowed non invasive soft tissue imaging and functional studies that transformed neurology and oncology.

Honors and Legacy

Shared the Nobel Prize in Physiology or Medicine in 2003 for MRI development and inspired broad adoption of MRI in clinical care.