Diffusion Imaging

Overview

Diffusion imaging measures water mobility to infer tissue microstructure. It is sensitive to acute ischemia and white matter integrity. Diffusion techniques include DWI and DTI among others.

Acute Stroke

Diffusion weighted imaging detects acute ischemic injury within minutes of onset. It guides reperfusion therapy decisions and prognosis. ADC maps help differentiate cytotoxic from vasogenic edema.

White Matter Tracts

Diffusion tensor imaging maps white matter tracts and connectivity. It aids in surgical planning and research on neurodevelopment and degeneration. Tractography supports preservation of critical pathways.

Advanced Methods

High angular resolution and multi shell acquisitions improve microstructural modeling. Quantitative diffusion metrics provide biomarkers for disease. Ongoing work refines acquisition and analysis standards.

Optical Coherence Tomography OCT

Overview

OCT provides micron scale cross sectional images of tissue microstructure widely used in ophthalmology and intravascular imaging.

Technique

Interferometric detection of backscattered light yields high resolution images. Catheter or probe based delivery adapts OCT to different organs.

Clinical Uses

Retinal layer assessment in ophthalmology and coronary plaque microstructure in cardiology.

Limitations and Safety

Limited penetration depth and need for clear optical window. Specialized probes required.