Introduction

SPECT CT combines functional SPECT imaging with anatomical CT to improve lesion localization and diagnostic specificity. Hybrid imaging enhances interpretation in oncology cardiology and infection imaging. Attenuation correction and anatomical correlation increase clinical confidence.

Clinical Applications

SPECT CT improves localization of sentinel nodes bone lesions and infection foci and refines cardiac perfusion assessment. It reduces equivocal findings and guides targeted interventions. Protocol optimization balances CT dose and diagnostic needs.

Technical Considerations

Accurate registration and attenuation correction require consistent patient positioning and timing between SPECT and CT acquisitions. Low dose CT protocols are often sufficient for localization while diagnostic CT may be used when additional anatomic detail is needed. Quality control ensures reliable hybrid performance.

Implementation

Hybrid SPECT CT systems require coordinated workflows radiopharmacy support and trained technologists for acquisition and reconstruction. Structured reporting integrates functional and anatomic findings for clinical teams. Ongoing training and protocol review maintain diagnostic quality.