Iodine 131 MIBG

Overview

Iodine 131 metaiodobenzylguanidine is a norepinephrine analog labeled with I 131 used for diagnostic imaging and targeted radiotherapy in select neuroendocrine tumors.

Properties

I 131 emits beta and gamma radiation enabling both therapeutic effect and gamma imaging; uptake reflects catecholamine transporter activity.

Uses

Used for localization and treatment of pheochromocytoma, paraganglioma and some neuroblastomas under specialized protocols.

Safety

Significant radiation dose requires inpatient isolation for therapy doses and strict radiological safety, thyroid blockade and patient counseling.

Molecular Radiotherapy

Overview

Molecular radiotherapy uses radiolabeled agents to treat disease. It delivers targeted radiation to tumors and other lesions. It combines diagnostic imaging with therapy planning.

Clinical Indications

Theranostic pairs match diagnostic tracers with therapeutic agents. Indications include neuroendocrine tumors and prostate cancer. Patient selection and dosimetry are critical for safety.

Delivery and Monitoring

Imaging monitors distribution and response to therapy. Dosimetry guides treatment planning and follow up. Multidisciplinary teams coordinate care and manage toxicity.

Future Prospects

New agents and delivery methods expand therapeutic options. Personalized dosimetry improves efficacy and safety. Research aims to broaden indications and access.

Physical Medicine and Rehabilitation

Overview

PM&R provides inpatient and outpatient rehabilitation including physical therapy occupational therapy and prosthetics to maximize patient independence.

Inpatient Rehab Units

Structured multidisciplinary programs address mobility pain management and activities of daily living with measurable functional goals.

Outpatient Therapy and Modalities

Therapists deliver exercise programs manual therapy and modalities such as ultrasound and electrical stimulation to support recovery.

Assistive Devices and Home Programs

Provision of orthoses prostheses and home exercise plans supports long term function and community reintegration.