Overview
Technetium 99m HMPAO is a lipophilic radiopharmaceutical used for brain perfusion imaging and for labeling leukocytes in infection imaging.
Properties
Tc 99m HMPAO crosses the blood brain barrier transiently and is retained in brain tissue proportional to regional blood flow; emits gamma photons for SPECT.
Uses
Used for cerebral perfusion SPECT in stroke and dementia evaluation and for leukocyte labeling to localize infection or inflammation.
Safety
Radiation exposure is low but present; follow nuclear medicine safety protocols and screen for pregnancy and breastfeeding.