Overview
Technetium 99m sestamibi is a lipophilic cationic radiopharmaceutical used for myocardial perfusion imaging and parathyroid adenoma localization.
Properties
Uptake depends on mitochondrial membrane potential and blood flow; emits gamma photons suitable for SPECT imaging.
Uses
Used for stress and rest myocardial perfusion SPECT, and for parathyroid imaging in selected protocols.
Safety
Consider radiation exposure, pregnancy screening and potential interactions with medications that affect tracer distribution.