Overview
Technetium 99m tilmanocept is a receptor targeted radiopharmaceutical designed for sentinel lymph node mapping by binding to mannose receptors in lymphatic tissue.
Properties
Small molecular construct labeled with Tc99m that is retained in sentinel nodes and provides high target to background ratio for planar and SPECT imaging.
Uses
Used for preoperative and intraoperative sentinel lymph node localization in breast cancer and melanoma staging.
Safety
Radiation exposure is low; follow injection technique and imaging timing recommendations to optimize localization and minimize false negatives.